Whitepapers

How to achieve scalable freezing & thawing of biopharmaceuticals

Impact of ice front growth speed on scalability of freezing protein solutions

This brochure covers modular set up for scaling down to 1mL, scaling up to 300L, and the shaker function.

Watson Marlow Fluid Technologies Solutions (WMFTS), fluid path solutions provider of peristaltic pumps and single-use component, outlines the results of a study which makes comparisons between the semi volatiles extractables profile of post-cured and non post-cured samples of its Pumpsil platinum-cured silicone tubing.

Reduce endotoxins in a sample to levels below the limit of detection for a LAL assay with an anion exchange resin in a flow-through chromatography mode.

Using the BioAccord LC-MS System and an Ambr® 15, we developed an analytical method for rapid mAb glycoform confirmations and mAb purity assessments. This unique method is high throughput capable and has the potential to be a fully automated platform for mid-process intraday monitoring of CQAs.

The need for flexible solutions for potent product handling is increasing. Check out our free whitepaper to discover best practices and innovative solutions available to you

ArmorFlex® Films are used in several of our products to provide high performance in powder handling and achieve greater efficiency than ever before.

Maximize yield without sacrificing quality, safety, or consistency. Discover ILC Dover flexible engineered solutions for #biopharm and #pharm manufacturing processes

Continuous liners reduce costs, cross-contamination, and operator labor. Watch the video to see how

ILC Dover announced its launch of liquid single-use bioprocessing bags, representing the first of many new products for handling sterile liquids in the biotherapeutics and cell and gene therapy markets. This expansion continues our line of solutions designed for use across the entire biotherapeutic and pharmaceutical manufacturing workflow—from powder containment and handling to sterile liquid handling and pre-filled liquid and powder bags.

soloPURE™ is ILC Dover's closed-barrier system for sterile manufacturing - learn more.

The JetMixer™ System provides fast powder mixing and complete protection of powder properties.

Precise temperature control has a significant influence on performance and quality in chemical process engineering. The Unistat range of temperature control systems ensure accurate temperatures and stable process conditions in research laboratories, pilot plants and kilolabs worldwide.

This technical bulletin discusses major regulatory updates, introduced by the FDA and EMA, regarding nitrosamines and SGS proposed risk assessment method for compliance.

Watson Marlow Fluid Technologies Solutions (WMFTS), fluid path solutions provider of peristaltic pumps and single-use component, outlines the results of a study which makes comparisons between the semi volatiles extractables profile of post-cured and non post-cured samples of its Pumpsil platinum-cured silicone tubing.

Improved host cell protein analysis using highly reproducible and scalable automated sample digestion and fractionation ahead of LC–MS coupled with iterative MS–MS

Automated MHC-I is associated peptide enrichment using the Agilent AssayMAP Bravo platform with large-capacity Protein A cartridges for immunopeptidomics analysis.

The AssayMAP Bravo was used to purify, digest, and clean up antibodies from 96 cell culture supernatants with high reproducibility and minimal labor prior to LC–MS.

Automated phosphopeptide enrichment from cell lysates with Fe(III)-NTA enables the identification of thousands phosphopepides with high reproducibly and selectivity.

Automated Antibody Drug Conjugate (ADC) purification and deglycosylation increases reproducibility and simplifies drug-to-antibody ratio (DAR) determination.

Automated sample prep and LC–MS peptide mapping approach to characterize and quantify multiple monoclonal antibody (mAb) critical quality attributes (CQAs)

Intact and subunit antibody mass determination was streamlined using automated purification and enzymatic cleavage and deglycosylation of immobilized antibodies.