Downstream Processing

Feliza Mirasol is the science editor for 

Articles

Viral clearance processes and guidance must evolve along with newer biotherapeutic modalities.

Updating Viral Clearance for New Biologic Modalities

Kilian Brand is lab technician downstream process development at 

Florian Capito is lab head downstream process development 

Verena Oeinck is lab technician downstream process development at 

Hendrik Flato is lab engineer downstream process development at Sanofi-Aventis Deutschland GmbH.

Marc Bisschops is director at Pall Medistad.

Martin Glenz is principal scientist at Pall GmbH.

Ralf Ehret is vice dean at Provadis School of International Management and Technology.

Continuous SEC was shown to increase productivity with the same product quality and yield.

Continuous Preparative SEC for Purification of “Difficult-to-Manufacture” Proteins–A Feasibility Study

The latest advances in downstream technologies include sterile disconnects for single-use manufacturing systems, ligand technologies for purifying RNA and for COVID-19 vaccines, and an automated perfusion system.

What’s New in Downstream Technologies 

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

A balance must be achieved between debris and impurity removal and maximizing product quality and yield.

Cell Harvesting Steps Separate the Good from the Bad

As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.

Technology Innovations Improve Process Chromatography Performance

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Chromatographic Science Clarifies Separation Challenges

Margaret (Peggy) Marino, PhD, is senior vice-president, Program Management, at AnaptysBio.

It is critical to evaluate specific considerations, from design to application, for the benefit of downstream bioprocessing and manufacturing.

Points to Consider for Continuous Downstream Bioprocessing

Jennifer Markarian is manufacturing editor of BioPharm International.

Filling and packaging of primary containers is a crucial piece of COVID-19 vaccine production.

CDMOs Build Fill/Finish Capacity for COVID-19 Vaccines

Sartorius adds chromatography systems and resins, tangential flow filtration, and biomolecular characterization technologies.

Sartorius Completes Acquisition of Select Danaher Brands

Pumps and other components meet the demands of single-use systems in biopharmaceutical downstream processing.

Manufacturing Equipment, Downstream Processing