Downstream Processing

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Articles

A balance must be achieved between debris and impurity removal and maximizing product quality and yield.

As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Margaret (Peggy) Marino, PhD, is senior vice-president, Program Management, at AnaptysBio.

It is critical to evaluate specific considerations, from design to application, for the benefit of downstream bioprocessing and manufacturing.

Jennifer Markarian is manufacturing editor of BioPharm International.

Filling and packaging of primary containers is a crucial piece of COVID-19 vaccine production.

Sartorius adds chromatography systems and resins, tangential flow filtration, and biomolecular characterization technologies.

Pumps and other components meet the demands of single-use systems in biopharmaceutical downstream processing.

GEA began supplying the new GEA Hilge Novatwin hygienic twin-screw pump line. 

Ensuring the quality of data in process monitoring and control systems starts in process development phases.

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.