Ready-to-use materials and in-line dilution can streamline overall bioprocessing operations.

Improving mAb Manufacturing Productivity

Process modeling can anticipate difficult aspects of a bioprocess.

Models for Success

Articles

This article will explore the traditional path from the laboratory to the clinic and how the fixed-bed technology provides an alternative solution to meet commercial demands.

Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines 

Process modeling offers an opportunity to troubleshoot for and anticipate difficult aspects of a bioprocess.

Using Process Modeling to Troubleshoot a Bioprocess

Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.

Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Therapies for early and late treatment and passive immunization of COVID-19 are needed and can be developed using antibodies from recovered patients.

Plasma-Based Antibody Therapies Battle Against COVID-19

Synthetic biology has advanced the scope and scale with which biologically derived therapeutics can be developed.

Biopharmaceutical Manufacturing and the Power of Synthetic Biology

New bioreactor designs, coupled with better media, process intensification and analytics, continue to improve upstream bioprocessing.

Bioreactors Redefine Upstream Productivity

The new BIOSTAT STR Generation 3 with BIOBRAIN bioproduction platform offers process intensification with automated feed and bleed and integrated cell retention functionality.

Sartorius Launches New Automated Single-Use Bioproduction Platform

Agnes Shanley is senior editor of Pharmaceutical Technology.

Better understanding and control of cell behavior is yielding benefits, upstream and beyond. 


Improving Upstream Predictability

The future of raw material sourcing for mAb production may lay in the sustainability of the source and the added benefits of newer technologies.


The Future of Raw Material Sources for mAbs

By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioprocessing.

Upstream Processing