Upstream Processing

Cell-free expression shows promise in preclinical applications but presents scale-up challenges.

Demand for recombinant microorganism-based cell culture supplements.

Biopharma responds to demand dynamics for upstream bioprocessing capacity.

June 02, 2021

Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.

May 19, 2021

VectorY, a Netherlands-based biotechnology company, has been selected as the European winner of MilliporeSigma’s 2021 Advance Biotech Grant Program.

May 02, 2021

Demand for recombinant microorganism-based cell culture supplements is rising on the back of lower contamination risk.

April 02, 2021

Biopharmaceutical companies and contract manufacturers respond to changing demand dynamics for upstream bioprocessing capacity.

April 02, 2021

The innovation of single-use technologies is applicable early on in the manufacturing process.

March 02, 2021

Overcoming time and cost constraints can help enable seed train intensification efforts to maximize product yield.

February 02, 2021

Connected, integrated bioprocessing enterprises with greater data analytics capabilities are coming.

January 02, 2021

Cell-culture optimization may see benefits from a synthetic biology-based approach that improves product titer, quality, and time.

December 02, 2020

Establishing an automated inline dilution system can potentially ease bottlenecking delays resulting from higher upstream yields.

November 02, 2020

PAT advances are enabling improved process understanding, process control, and error prevention.