Upstream Processing

SUBs Prove Mettle Amid Growing Demand

Large-scale SUBs prove successful as limits are tested.

Bioanalytical Studies Support Biosimilars Approval Pathway

Bioassay studies for biosimilars enables regulatory pathway.

Cell-free Expression Systems Offer Alternatives

Cell-free expression shows promise in preclinical applications but presents scale-up challenges.

Recombinant Supplements Offer Lower Contamination Risk

Demand for recombinant microorganism-based cell culture supplements.

Recent Trends in Data Analytics for Upstream Process Workflows

January 02, 2022

Modeling techniques can improve process control and monitoring in biopharmaceutical production.

Automating Upstream Processes Helps Sync Workflows

January 02, 2022

Upstream processing is better optimized with the help of automated workflows.

FUJIFILM Irvine Scientific Opens New European Manufacturing Facility

December 16, 2021

FUJIFILM Irvine Scientific’s new manufacturing facility in Tilburg, the Netherlands, is now fully operational.

Sartorius Launches Expansion in South Korea with Mullti-Million Dollar Investment

December 02, 2021

Sartorius will invest approximately €270 million (US$305 million) to expand its biopharmaceutical manufacturing activities in South Korea’s biopharm hub.

Lonza Invests in Microbial Development Lab Expansion

November 18, 2021

Lonza is expanding its microbial development capabilities at its Visp, Switzerland, site to support clinical and commercial drug development programs.

Perfusion Cell Culture is Gaining Ground Upstream

November 02, 2021

The adoption of perfusion cell culture continues to advance with the help of PAT tools.

Large-Scale Single-Use Bioreactors Prove Mettle Amid Growing Demand

October 02, 2021

Large-scale single-use bioreactors prove successful as limits are tested.

Limits and Successes Define Large-Scale SUBs Path

October 01, 2021

SUB bioreactor performance has had seen its limits and successes.

Bioprocessing Innovations Pose New Challenges for Fermentation

September 02, 2021

Advancements in bioprocessing technologies test microbial fermentation adaptability.

Single-Use Technologies Prove Effective for Viral Vector Process Development

August 02, 2021

The benefits of single-use technologies for upstream viral-vector processes clearly outweigh their disadvantages.