Manufacturing, Nucleic Acids

CureVac Receives Funding, Collaborates with GSK on mRNA and mAbs

July 21, 2020

GSK and CureVac will collaborate on mRNA-based vaccines and mAbs. Separately, the EIB and others provided CureVac with financing for development of its CVnCoV vaccine candidate and expansion of manufacturing.

Source of Nucleic-Acid Asymmetry May Advance Gene Therapy

July 01, 2019

Research from the Institute for Research in Biomedicine offers insight into the source of asymmetry between nucleic acid hybrids.

Partnership to Address Pandemic Viral Outbreaks

May 10, 2019

AbCellera, Niaid Vaccine Research Center, and Ichor Medical Systems have formed a partnership to develop an end-to-end platform capable of developing field-ready, nucleic acid-based countermeasures against a pandemic strain of influenza.

FDA Approves First-of-its-Kind RNA Therapy

August 13, 2018

The new drug, Onpattro (patisiran), by Alnylam Pharmaceuticals, is in a new class of drugs called small interfering ribonucleic acid (siRNA) treatment.

Hydroxyapatite Chromotography Media Offers Enhanced Biomolecule Purification

July 18, 2018

The media, by Tosoh Bioscience, is composed of calcium and phosphate buffers and offers mixed-mode properties for biomolecule purification.

Moderna Opens Manufacturing Site for mRNA Therapeutics

July 17, 2018

Moderna’s new manufacturing plant in Norwood, MA gives the company capacity for preclinical and Phase I and II clinical manufacturing for its mRNA development candidates, including personalized cancer vaccines.

Vectalys, FlashCell Merge to Form Gene Therapy Company

May 23, 2018

The new company will develop proprietary RNA-based therapeutics and will provide broad lentiviral development and manufacturing expertise and support.

Boehringer Ingelheim and Roche Collaborate on Treatment for Inflammatory Bowel Diseases

January 05, 2018

The companies aim to discover and develop locked nucleic acid oligonucleotides as orally available therapies for treating inflammatory bowel diseases.

Nitto Avecia Completes Large-Scale Synthesis of Oligonucleotide

November 13, 2017

Company completes first successful run of what is believed to be the largest synthesis-scale done for oligonucleotide APIs.

Cobra Biologics Expands Gene Therapy Manufacturing Operations

April 18, 2017

Cobra will increase capacity in response to customer demand for DNA and viral vector production.