Manufacturing

Feliza Mirasol is the science editor for 

Chris Spivey is the editorial director of 

Videos

In this episode of Drug Digest, Pharmaceutical Technology editors discuss the advantages and savings that continuous manufacturing may offer as well as the very real obstacles that might make a fully continuous process not feasible, especially in biologics manufacturing.

Drug Digest: Advancements in the Implementation of Continuous Manufacturing

Articles

A CPHI North America panel discussion forewarns that CDMO supply chains are potentially the biggest single risk to product resilience. 

Suppliers’ Supply Chains and Continuous Manufacturing Pose Big Risks for US CDMOs

Hovione has expanded its drug product offering with a new manufacturing line dedicated to continuous tableting.

Hovione Expands its Continuous Manufacturing Offering and Services

The adoption of perfusion cell culture continues to advance with the help of PAT tools.

Perfusion Cell Culture is Gaining Ground Upstream

Agnes Shanley is senior editor of Pharmaceutical Technology.

As downstream bioprocessing improvements continue, efforts are underway to integrate downstream processes into continuous operations. 

Moving Closer to End-to-End Continuous Bioprocessing

Garima Thakur is a graduate student in the Department of Chemical Engineering at the Indian Institute of Technology New Delhi.

Anurag S. Rathore is a professor in the Department of Chemical Engineering at the Indian Institute of Technology Delhi and a member of 

l's Editorial Advisory Board, Tel. +91.9650770650, asrathore@biotechcmz.com.

The need for real-time monitoring and control has spurred the development of new analytical tools.

Near Infrared Spectroscopy as a Versatile PAT Tool for Continuous Downstream Bioprocessing

Sanofi’s Digitally Enabled Integrated Continuous Biomanufacturing Facility in Framingham, MA was named the Overall Award winner at the ISPE virtual annual meeting. 

Sanofi Wins ISPE FOYA Overall Award

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

PAT advances are enabling improved process understanding, process control, and error prevention.

Control Strategies for Perfusion Cell Culture

Margaret (Peggy) Marino, PhD, is senior vice-president, Program Management, at AnaptysBio.

It is critical to evaluate specific considerations, from design to application, for the benefit of downstream bioprocessing and manufacturing.

Points to Consider for Continuous Downstream Bioprocessing

Better understanding and control of cell behavior is yielding benefits, upstream and beyond. 


Manufacturing, Continuous Biologics Processing