DO Control PID Tuning for Cell Culture Applications

The proportional–integral–derivative (PID) control mechanism is used for a variety of processes, including dissolved oxygen (DO) control. This protocol introduces a method developed to optimize the PI values on Eppendorf bioprocess controllers.

Vero Cell Cultivation for Vaccine Production

***Live: Thursday, Oct. 22, 2020 at 10am EDT| 9am CDT| 3pm BST| 4pm CEST***Process development for anchorage-dependent cells at bench scale is crucial to establish cost-efficient workflows in larger volumes. Learn how different process parameter can be monitored and controlled in a perfusion bioprocess and the potential of using packed-bed bioreactors or a microcarrier spin filter for attachment cell-based vaccine production.. *** On demand available after final airing until Oct. 22, 2021.***

Bioprocess for Beginners: From Shaker to Bioreactor

• Using stirred-tank bioreactors for stem cell culture provides advantages. • Factors to consider include OTR, agitation speed, and impeller blades. • An eight-blade impeller can address challenges associated with scale-up.