Peer-Reviewed Research

Understanding Commercial Cell Culture Process Performance Variation Through Advanced Data Analytics

June 01, 2020

Advanced data analytics, including statistical modeling and machine learning technique, can enable more efficient and reliable bioprocesses.

Therapeutic Potential of Green, Synthesized Gold Nanoparticles

January 01, 2020

This study aims to use plant-leaf extract for the green synthesis of gold nanoparticles and to evaluate their antibacterial and antioxidant activity.

Catalytic Site Analysis and Characterization of a Solvent-Tolerant Aldo-Keto Reductase

July 01, 2019

In this study, a novel aldo-keto reductase was cloned and purified, and its important conserved sites were analyzed.

Comparing Facility Layout Options for Managing Business and Operating Risks

June 01, 2019

The authors present a risk analysis of the impact of various business and operating risks on three facility layout strategies.

Efficacy of a Simple Static Cleaning Procedure for SPTFF

January 01, 2019

A key technology that can help achieve a continuous production flow is single-pass tangential flow filtration.

Separation and Purification of a Tissue-Type Plasminogen Activator from Trichoderma reesei

December 01, 2018

This research proposes a method for separating and purifying tissue-type plasminogen activator from a fungal cell source.

Single-Use Mixing Technology for Virus Clearance (Part 2: Compatibility, Leachables, and Scale-Up Studies)

November 01, 2018

The second half of this article describes the testing methods used by the authors to demonstrate the applicability of single-use mixing technology for virus inactivation.

Ensuring Viral Safety of Viral Vaccines and Vectors

September 01, 2018

Viral vaccines and viral vectors used in biotherapeutic applications carry the risk of microbial contamination, which must be addressed.

Study on an Inactivation Evaluation Method of Cleaning Processes for Biopharmaceuticals

September 01, 2018

This study was successful in establishing a reliable and effective method for evaluating cleaning processes based on risk. Click here to view a PDF of this article.

NIST Spectroscopic Measurement Standards

May 01, 2018

The National Institute of Standards and Technology (NIST) has developed Standard Reference Material (SRM) 2082 as a pathlength standard for UV absorbance measurements for use with the new generation of microvolume spectrophotometers and short-pathlength cuvettes.