Demand for greater process efficiency drives technology development.

Clarifying Separation Needs

Topic

Articles

As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.

Technology Innovations Improve Process Chromatography Performance

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Chromatographic Science Clarifies Separation Challenges

Margaret (Peggy) Marino, PhD, is senior vice-president, Program Management, at AnaptysBio.

It is critical to evaluate specific considerations, from design to application, for the benefit of downstream bioprocessing and manufacturing.

Points to Consider for Continuous Downstream Bioprocessing

Jennifer Markarian is manufacturing editor of BioPharm International.

Filling and packaging of primary containers is a crucial piece of COVID-19 vaccine production.

CDMOs Build Fill/Finish Capacity for COVID-19 Vaccines

Identifying the source, assessing the risk, and removing residual impurities requires a strategic approach.

Eliminating Residual Impurities Starts with a Strategic Plan

Tools such as manufacturing execution systems, artificial intelligence, and software innovations are useful for enhancing data integrity protection.

Challenges, Tools, and Strategies for Data Integrity Protection

Sartorius adds chromatography systems and resins, tangential flow filtration, and biomolecular characterization technologies.

Sartorius Completes Acquisition of Select Danaher Brands

The latest advances in downstream technologies include a fluid chromatography system, sensing and control units for hygienic valves, a compact valve platform, a membrane purification column, and a protein A affinity chromatography resin.

What’s New in Downstream Technologies

Ensuring the quality of data in process monitoring and control systems starts in process development phases.

Building Data Quality in Generates Quality Data Out

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.

Downstream Processing