Downstream Processing

July 01, 2020

Identifying the source, assessing the risk, and removing residual impurities requires a strategic approach.

June 01, 2020

Tools such as manufacturing execution systems, artificial intelligence, and software innovations are useful for enhancing data integrity protection.

May 01, 2020

Sartorius adds chromatography systems and resins, tangential flow filtration, and biomolecular characterization technologies.

April 01, 2020

The latest advances in downstream technologies include a fluid chromatography system, sensing and control units for hygienic valves, a compact valve platform, a membrane purification column, and a protein A affinity chromatography resin.

March 02, 2020

Ensuring the quality of data in process monitoring and control systems starts in process development phases.

February 01, 2020

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.

January 01, 2020

Achieving effective manufacturing processes and sufficient capacity remains a top priority across a diversified biologic drug pipeline.

January 01, 2020

While cell and gene therapies differ in many ways, some of the best practices for process development and validation are similar.

January 01, 2020

Temperature-sensitive biologics are lyophilized to preserve therapeutic viability, but the process presents complexities and challenges that are as yet not fully understood.

December 01, 2019

Ensuring that viral vectors are free of viral contaminants requires a focus on prevention and control.