The authors evaluated the potential of direct filtration for multiple biopharmaceutical candidates. This article is Part 2 of the study.

Fouling Mechanisms of Filters in the Harvest Development of Monoclonal Antibody Therapeutics—Pt 2

The authors present a methodology to assess the contribution of individual filters to overall capacity of the direct filtration train, and elucidate how capacity is affected by characteristics of the cell culture broth and process parameters.

Fouling Mechanisms of Filters in the Harvest Development of Monoclonal Antibody Therapeutics—Pt 1

SUS aids biopharma manufacturers to overcome the rigidity of more traditional stainless-steel technologies.

Stepping Up Process Control with Single-Use Systems

Topic

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Articles

Collaboration between technology providers and biopharma manufacturers are enabling both evolutionary and novel developments.

Advances in Filtration Technology

Downstream processes may be streamlined by using automation.

Automation Downstream Controls Quality

Automation technologies used in the development and manufacture of biopharmaceuticals continue to evolve, providing the potential for reduced costs and time.

Streamlining Bioprocesses with Automation

Feliza Mirasol is the science editor for 

Freudenberg Medical now offers custom single-use assemblies to expand its offerings in silicone extrusion and molding for biopharma applications.

Freudenberg Adds Custom Single-Use Assemblies to Biopharma Product Portfolio

Webcasts

Webinar Date/Time: Wed, Jul 24, 2024 12:00 PM EDT

Guide Decisions through Drug Development: Localize Critical PTMs at the Sub-Unit Level

Ecolab Life Sciences and Repligen introduce DurA Cycle, a new affinity resin for large-scale biologics manufacturing.

Ecolab Life Sciences and Repligen Launch New Affinity Resin for Commercial Biologics Manufacturing

The biopharma industry is looking at continuous chromatography for sensitive molecules.

Evaluating the Use of Continuous Chromatography

Webinar Date/Time: Wed, Jun 19, 2024 11:00 AM EDT

Achieve Scalable and High Recovery in rAAV Harvest Process

Robust Oligonucleotide Molecular Weight Confirmation by LC-MS

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Thu, Jun 13, 2024 11:00 AM EDT

Downstream Processing

Fouling Mechanisms of Filters in the Harvest Development of Monoclonal Antibody Therapeutics—Pt 2

Fouling Mechanisms of Filters in the Harvest Development of Monoclonal Antibody Therapeutics—Pt 1

Stepping Up Process Control with Single-Use Systems