Downstream Processing

Innovative Resins Can Improve Purity and Quality

Chromatography resins offer promising advantages in downstream bioprocessing.

Moving Closer to End-to-End Continuous Bioprocessing

Efforts are underway to integrate downstream processes into continuous operations.

Using AEX Membrane Adsorbers for Virus Clearance

Spiking studies evaluated a range of critical processing conditions.

Cytiva Acquires German Software Maker GoSilico

June 02, 2021

GoSilico’s software for digital twins of downstream biopharmaceutical processes will be integrated into Cytiva.

Innovative Chromatography Resins Can Improve Purity and Quality

June 01, 2021

Recent innovations in chromatography resins offer promising advantage in downstream bioprocessing.

Moving Closer to End-to-End Continuous Bioprocessing

May 01, 2021

As downstream bioprocessing improvements continue, efforts are underway to integrate downstream processes into continuous operations.

Sartorius Opens New Downstream Center of Excellence Facility in UK

April 16, 2021

Sartorius has expanded in the United Kingdom with the relocation to a new facility in Havant, Hampshire, for downstream processing equipment.

Using Anion Exchange Membrane Adsorbers to Ensure Effective Virus Clearance of Challenging Parvoviruses

April 02, 2021

A series of minute virus of mice spiking studies were performed with a monoclonal antibody product and small-scale AEX membrane adsorbers to evaluate a range of critical processing conditions.

Fluid Handling Systems are Seeing Benefit from Single-Use Technologies

April 01, 2021

The adoption of single-use technologies in fluid-handling systems helps streamline downstream bioprocessing operations.

Near Infrared Spectroscopy as a Versatile PAT Tool for Continuous Downstream Bioprocessing

March 02, 2021

The need for real-time monitoring and control has spurred the development of new analytical tools.

A Unified Approach for Scaling Bioprocess Unit Operations

February 01, 2021

A unified scale-up approach, as presented here, can be applied to any unit operation.

Meeting Fill/Finish Challenges for COVID-19 Vaccines

February 01, 2021

CDMOs address the unique challenges of liquid and lyophilized forms as well as preparing for the large capacity needed for COVID-19 vaccines.

Cytiva Advances Fiber Chromatography Technology with New Launch

January 28, 2021

The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.