Multi-Column Chromatography for mAb Capture and Viral Clearance
July 09, 2024
Traditionally, producing biotherapeutics such as monoclonal antibodies required a multi-step process
to remove impurities, including host-cell proteins, DNA, adventitious viruses, and antibody aggregates. However, by
converting the process from batch chromatography to multi-column chromatography (MCC), there is potential to
reduce costs and shorten production times for the capture and purification of high-quality mAbs.