Manufacturing, Separation and Purification

Challenges in Vector Purification for Gene Therapy

February 01, 2020

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.

Using TEM-Based Image Analysis to Validate the Presence of HA Spikes on Influenza VLPs

November 01, 2019

The authors of this study demonstrate an innovative method that is useful and complements traditional HA assays.

JSR, PeptiDream Partner on Development Program for Affinity Chromatography

September 23, 2019

The companies will focus on identifying peptides applicable to the affinity chromatography process used in the purification of biopharmaceuticals.

BIA Separations Launches AAV Process Development Service to Accelerate Gene Therapy Production

September 19, 2019

The new program, Cornerstone, integrates process development expertise and novel technology to remove development bottlenecks in the manufacture of gene therapy medicinal products.

Enhancing Cell Harvest

August 01, 2019

Higher cell densities are driving innovations in harvesting, including closed systems for intensified processes.

Single-Use for Downstream Chromatography: Benefit or Hindrance?

May 01, 2019

Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.

Watson-Marlow Demonstrates Quantum Peristaltic Pump at INTERPHEX 2019

April 05, 2019

The company’s Quantum peristaltic pump uses a patented single-use cartridge technology and is applicable to downstream bioprocessing.

Biologic Drug Manufacturing Capacity on the Agenda for INTERPHEX 2019 Keynote Series

April 03, 2019

Pharmaceutical Technology and BioPharm International will present a Keynote Session on Meeting Bioprocessing Manufacturing Capacity Demands on Wednesday, April 3, 2019, during INTERPHEX 2019 at the Javits Center in New York City.

Cleaning Chromatography Resin Residues from Surfaces

April 01, 2019

Laboratory test methods evaluate cleaning agents and cleaning process design for removing resin residues from the surfaces of non-dedicated chromatography columns systems.

Membrane Technology for Enhancing Separation and Purification

March 01, 2019

Downstream process equipment for mAbs manufacturing must be designed to fit technology developments in upstream processes.