Downstream Processing

Articles

As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.

Technology Innovations Improve Process Chromatography Performance

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Chromatographic Science Clarifies Separation Challenges

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.

Challenges in Vector Purification for Gene Therapy

The authors of this study demonstrate an innovative method that is useful and complements traditional HA assays.

Using TEM-Based Image Analysis to Validate the Presence of HA Spikes on Influenza VLPs

The companies will focus on identifying peptides applicable to the affinity chromatography process used in the purification of biopharmaceuticals. 

JSR, PeptiDream Partner on Development Program for Affinity Chromatography

The new program, Cornerstone, integrates process development expertise and novel technology to remove development bottlenecks in the manufacture of gene therapy medicinal products.

BIA Separations Launches AAV Process Development Service to Accelerate Gene Therapy Production

Jennifer Markarian is manufacturing editor of BioPharm International.

Higher cell densities are driving innovations in harvesting, including closed systems for intensified processes.

Enhancing Cell Harvest

Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.

Single-Use for Downstream Chromatography: Benefit or Hindrance?

The company’s Quantum peristaltic pump uses a patented single-use cartridge technology and is applicable to downstream bioprocessing.

Watson-Marlow Demonstrates Quantum Peristaltic Pump at INTERPHEX 2019

Pharmaceutical Technology and BioPharm International will present a Keynote Session on Meeting Bioprocessing Manufacturing Capacity Demands on Wednesday, April 3, 2019, during INTERPHEX 2019 at the Javits Center in New York City.

Manufacturing, Separation and Purification