Manufacturing, Separation and Purification

Purification of Antibodies Using Novel Convecdiff Membranes Part 1: Providing High Binding Capacity at Short Residence Time and Low Pressure Drops

January 02, 2023

The testing of new convecdiff membranes shows this material to be well suited for lab- and commercial-scale bind-and-elute applications.

Viral Clearance Studies: Challenges and Beyond

December 02, 2022

The design of viral clearance studies must keep pace with the quickly evolving biologic drugs industry.

Advancing Process Chromatography in DSP

June 01, 2022

Thanks to technological advances, process chromatography challenges are surmountable, but increasingly complex therapies in the pipeline will demand more efficient processes in the future.

Driving Efficiencies in DSP Separation and Purification

May 03, 2022

An increasingly complex development pipeline and industry considerations, such as sustainability, are leading to a greater need for more efficient separation and purification in downstream processing.

What’s New in Downstream Processing?

April 01, 2022

The past year of downstream processing has brought innovations in pH sensitive antibody purification, single-use fermentation separators, and more.

Demonstrating a Fully Continuous Bioprocess

March 03, 2022

Flexible and efficient methods are needed for biopharmaceutical manufacturing.

Considering Purification and Separation in the Downstream Train

March 01, 2022

Emerging drug classes are giving rise to challenges in downstream processing, pushing the need for strategizing efficiencies.

Enhancing Resins Addresses Purification Concerns

January 02, 2022

Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecules.

Defining a Holistic Approach to mAb Purification Processes

July 02, 2021

Understanding the process and product goals is just the first step to a holistic approach to process development.

Viral Clearance Testing Increasingly Challenged by New Biologic Modalities

July 01, 2021

New biologic modalities, such as cell and gene therapies, pose increasing difficulties in viral clearance testing methods.