Manufacturing, Separation and Purification

Cytiva Advances Fiber Chromatography Technology with New Launch

January 28, 2021

The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.

EASY: a Disruptive mAb Purification Process to Reduce Cost of Goods

January 02, 2021

The development of an innovative purification process simplifies downstream processing for biologics.

Using Automated Inline Dilution to Ease Bottlenecking

December 02, 2020

Establishing an automated inline dilution system can potentially ease bottlenecking delays resulting from higher upstream yields.

Updating Viral Clearance for New Biologic Modalities

December 02, 2020

Viral clearance processes and guidance must evolve along with newer biotherapeutic modalities.

Continuous Preparative SEC for Purification of “Difficult-to-Manufacture” Proteins–A Feasibility Study

November 02, 2020

Continuous SEC was shown to increase productivity with the same product quality and yield.

Wyatt Technology Launches a New Line of Separation Instrumentation and Software for Analytes

October 22, 2020

The 6th-generation Eclipse FFF system handles analytes such as proteins, polymers, viruses, gene vectors, and liposomal drug nanoparticles.

Cell Harvesting Steps Separate the Good from the Bad

October 01, 2020

A balance must be achieved between debris and impurity removal and maximizing product quality and yield.

Technology Innovations Improve Process Chromatography Performance

September 01, 2020

As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.

Chromatographic Science Clarifies Separation Challenges

August 02, 2020

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Challenges in Vector Purification for Gene Therapy

February 01, 2020

Developers need to transcend the limits of existing separation technologies, to maximize vector recovery while preserving therapeutic potency.