Thermo Fisher Scientific

Articles

Cell Culture Media Metabolite Profiling

Use an HRAM LC-MS approach to cell culture media metabolite profiling to develop a targeted quantitative assay that monitors and quantifies multiple classes of cell culture media metabolites simultaneously in a single LC-MS run. Demonstrate that the developed quantitative assay can be used to support upstream processing optimization and quality control with excellent quantitative performance, high throughput and robustness.

Use of a MAbPac RP capillary column to monitor glycosylation site occupancy in therapeutics

A new approach using the novel, easy-to-connect Thermo Scientific MAbPac RP capillary column for determining glycosylation site occupancy of therapeutic antibodies from the analysis of their tryptic digest.

Technology Forum Series: Strategies to Prevent Drug Shortages and Resolve Capacity Challenges.

***Session 1: Thursday, April 22, 2021, 10am EDT, Session 2: Thursday, April 22, 2021, 11am EDT, Session 3: Thursday, April 22, 2021, 1pm EDT*** A drug’s journey from development to manufacturing to patients is paved with roadblocks and potholes; many threats can derail bio/pharmaceutical processes. Potential solutions to such pitfalls have been discussed for years; however, few manufacturers have embraced technology and process advances to proactively ensure drug supply chain continuity.