Manufacturing

Articles

The acquisition of Intermountain Life Sciences will double Cytiva’s capacity for buffers and liquid cell culture media at its manufacturing site in Logan, Utah.

Cytiva Acquires Intermountain Life Sciences

Feliza Mirasol is the science editor for 

Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.

Cell-free Expression Systems Pose Cell Culture Alternative

Demand for recombinant microorganism-based cell culture supplements is rising on the back of lower contamination risk.

Recombinant Supplements Offer Lower Risk of Cell Culture Contamination

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Biopharmaceutical companies and contract manufacturers respond to changing demand dynamics for upstream bioprocessing capacity.

Maximum Output Starts with Optimized Upstream Processing

The innovation of single-use technologies is applicable early on in the manufacturing process.

Single-Use Bags Help Maintain Aseptic Ingredient Transfer to Bioreactors

Overcoming time and cost constraints can help enable seed train intensification efforts to maximize product yield.

Jumping Seed Train Intensification Hurdles to Maximize Yield

Establishing an automated inline dilution system can potentially ease bottlenecking delays resulting from higher upstream yields.

Using Automated Inline Dilution to Ease Bottlenecking

PAT advances are enabling improved process understanding, process control, and error prevention.

Control Strategies for Perfusion Cell Culture

An innovation such as synthetic biology can develop a consistently stable starting cell line for cell therapy source material.

Synthetic Biology Offers a Solution to Cell Therapy Source Material Constraints

Melisa Carpio is a global technology consultant for Cell Culture Technologies at Sartorius North America.

Bioreactor technology advances can offer seamless manufacturing scale-up and can reduce the timeline and cost of biologics production.

Manufacturing Equipment, Upstream Processing