Manufacturing Equipment, Upstream Processing

Using Process Modeling to Troubleshoot a Bioprocess

August 02, 2020

Process modeling offers an opportunity to troubleshoot for and anticipate difficult aspects of a bioprocess.

Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow

July 02, 2020

BioPharm International

Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.

Biopharmaceutical Manufacturing and the Power of Synthetic Biology

May 01, 2020

BioPharm International

Synthetic biology has advanced the scope and scale with which biologically derived therapeutics can be developed.

GEA Launches New Twin-screw Pumps for Hygienic Applications

March 20, 2020

GEA began supplying the new GEA Hilge Novatwin hygienic twin-screw pump line.

Sartorius Launches New Automated Single-Use Bioproduction Platform

March 09, 2020

The new BIOSTAT STR Generation 3 with BIOBRAIN bioproduction platform offers process intensification with automated feed and bleed and integrated cell retention functionality.

Cell Culture Variables for Gene Therapy Vectors

February 01, 2020

BioPharm International

The production of viral vectors for use in gene therapy benefits from being able to use similar cell-culture processes as mAbs, but it faces limitations under current cell-culture technologies.

Single-Use Bioreactors: To Scale Up or Scale Out?

January 01, 2020

BioPharm International

Industry experts debate the pros and cons of “going bigger” than the 2000-L industry norm in a single vessel.

What’s New in Manufacturing: Upstream Technologies

December 06, 2019

The latest advances in upstream technologies include single-use equipment and a protein analyzer for titer monitoring, as well as new plasmid DNA manufacturing capability.

The Evolving Role of Starting Materials in Cell and Gene Therapy

December 01, 2019

BioPharm International

Accelerated approval pathways and growing demand for cell and gene therapies are putting pressure on providers of cellular starting materials, and they must ensure a steady supply.

Cell-Culture Advances Test Bioreactor Performance Models

September 01, 2019

BioPharm International

The evolution of cell-culture technology is driving the need for improvements in modeling solutions.