Podcasts

The past few years have been filled with seminars discussing viruses, with COVID-19 stealing most of the headlines. Not all viruses are created equal; some are actually beneficial for human health and biotherapeutics delivery. Adeno-associated virus (also referred to as AAV) vectors fall into this category. AAVs are “hot” right now, as they are currently one of the most promising systems for human gene therapy. There are many types of AAVs and purification and analysis of these types of viruses can present challenges. In this dedicated dialogue, we will discuss the most efficient workflow for AAV purification and analysis.

An Efficient Workflow for AAV Purification and Analysis

Choosing the right sterilization technique for your drug product and its packaging is not always a simple decision. While most packaged drug products have specific requirements, newer sterilization techniques offer innovative ways of ensuring sterility that may be more suitable than standard sterilization processes. In this dedicated dialogue, the audience will learn about standard sterilization processes, be introduced to newer techniques, and understand how these techniques have been applied to parenteral packaging components.

Innovation in Sterilization Techniques for Parenteral Packaging

Building Biotech Series

Astrea Bioseparations joins Biopharm International for a discussion about the evolving challenges of downstream processing for advanced therapies, and what the future might hold. We talk about the company’s evolution over the last three decades, including the Discover. Develop. Deliver. approach to customer alignment. The latest industry trends are reviewed, along with considerations to keep in mind during the selection of off the shelf or customized downstream solutions. 

Developing Cost-effective, Accelerated Downstream Processes

The entire clinical supply chain — from manufacturer to shipper to clinician to patient — is united in its reliance on cold chain solutions to consistently deliver quality of life and potentially lifesaving treatments. Learn more about how to navigate a vast array of temperature-controlled shipping options across five specific temperature ranges while ensuring product integrity and patient safety. 

Lifesaving Logistics: Today's Cold Chain

In this podcast, Catalent Biologics regulatory expert, Kelly Davis shares her insights on why companies choose to repurpose drugs, what the main considerations are when doing so, how companies can overcome the challenges they face, and how Catalent supports companies going through this process.  

Repurposing Drugs for New Indications 


Inline dissolved CO2 measurement & monitoring during cell culture and fermentation scale up offers significant benefits for process control, impacting productivity and quality attributes. Real-time dCO2 measurement complements routine dissolved CO2 measurements with a BGA during pre-clinical and commercial operations. This podcast explains why dCO2 should be measured as a critical process parameter, what actions can be taken based on dCO2 measurements, and how to implement real-time dCO2 measurement.


Monitoring & Controlling dCO2 in Cell Culture & Fermentation

The Critical Role of CE-MS Methods for Biotherapeutic Characterization with Scott Mellors, Ph.D.


In this podcast, we speak with Austin Mogen, Ph.D., Sr. Field Application Scientist and Cat Siler, Ph.D., Field Application Scientist both from Corning Life Sciences about the available platforms for adherent cell culture scale-up. These platforms offer the potential to reduce time and cost while delivering high efficiency for a variety of adherent applications. 


The Race to Billions How Amplifying Adherent Cultures Can Get You There

Cell therapy market has been experiencing double digit growth in recent years stemming from the promising success of the first autologous CAR-T products. However, manufacturing these therapies at scale continues to be a challenge. This podcast will focus on the specialized needs of manufacturing cell therapies at scale and how Custom Manufacturing Organizations are stepping in to drive process efficiencies and standardization. 

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