Manufacturing, Process Chromatography

Tools and Technologies for Robust Method Lifecycle Management in Liquid Chromatography

January 11, 2023

Advanced LC technologies can streamline the review process for LC equipment maintenance.

Choosing the Right Resins for Viral Vector Affinity Chromatography

January 02, 2023

Affinity chromatography resins must perform well under mild elution conditions yet withstand robust cleaning and sanitization protocols.

Removing Residual Impurities

November 02, 2022

A thorough knowledge of both the upstream and downstream processes is required to ensure effective removal of residual impurities in biopharmaceuticals.

Quality by Design for Affinity Chromatography

July 01, 2022

Enriching process understanding enables robust process controls.

Advancing Process Chromatography in DSP

June 01, 2022

Thanks to technological advances, process chromatography challenges are surmountable, but increasingly complex therapies in the pipeline will demand more efficient processes in the future.

Considering Purification and Separation in the Downstream Train

March 01, 2022

Emerging drug classes are giving rise to challenges in downstream processing, pushing the need for strategizing efficiencies.

Enhancing Resins Addresses Purification Concerns

January 02, 2022

Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecules.

Thermo Fisher Launches New Mass Spectrometry and Chromatography Solutions

November 03, 2021

Thermo Fisher Scientific showcases its new mass spectrometry and chromatography solutions at the ASMS Conference on Oct. 31–Nov. 4, 2021.

Process Chromatography Makes Steady Progress

September 01, 2021

Process chromatography in downstream processing has seen steady improvements over the years, but there is still room for improvement.

Using Digital Twins to Model Process Chromatography

September 01, 2021

Mechanistic models provide process understanding for developing robust manufacturing processes and for scale up and tech transfer.