Manufacturing, Process Chromatography

Ecolab Life Sciences and Repligen Launch New Affinity Resin for Commercial Biologics Manufacturing

June 13, 2024

Ecolab Life Sciences and Repligen introduce DurA Cycle, a new affinity resin for large-scale biologics manufacturing.

Evaluating the Use of Continuous Chromatography

June 08, 2024

The biopharma industry is looking at continuous chromatography for sensitive molecules.

Additives Play a Role in Removal of Empty and Partial AAV Capsids (ASGCT 2024)

May 08, 2024

Experiments conducted by the downstream technology team at Spark Therapeutics involving metal ion-containing additives showed improved capsid clearance in AAV production.

Fouling Mechanisms of Filters During the Harvest Development of Monoclonal Antibody Therapeutics with Intensified Upstream Processes—Part 2

March 02, 2024

The authors evaluated the potential of direct filtration for multiple biopharmaceutical candidates. This article is Part 2 of the study.

Purolite and Repligen Launch New Affinity Resin

February 07, 2024

Purolite and Repligen have commercially launched a new CH1 affinity resin for the purification of specialized mAbs.

Selecting Chromatography Resins for Bispecific Antibody Purification

January 01, 2024

Product and process understanding are essential to effective resin selection.

3M Health Care Launches New Chromatographic Clarifier

November 15, 2023

The 3M Harvest RC Chromatographic Clarifier, BT500 is the latest addition to the company’s chromatographic clarifier portfolio.

Innovations in Downstream Processing

September 01, 2023

Innovations in downstream processing accelerate development, enhance efficiency, and promote sustainability.

Exploring How CPC Progresses Green Chemistry Practices

July 01, 2023

CPC presents a green alternative to chromatography that supports sustainable operations.

Determining and Optimizing Dynamic Binding Capacity

April 02, 2023

The breakthrough approach is commonly used, but the devil is in the details.