Formulation and Drug Delivery, Liquids

Vetter Expands in Asia-Pacific

November 09, 2017

The company has officially opened a local brand office in South Korean to support its existing business in the region.

Delivering Biologics in Prefilled Syringes

November 01, 2017

BioPharm International

Siliconization is a key process step in the manufacturing of prefilled syringe systems.

Lilly to Invest $72 Million for Insulin Manufacturing Upgrade

October 23, 2017

The $72-million investment, part of a larger $850-million investment into its US operations, will allow the drugmaker to replace an outdated insulin vial-filling line and to upgrade technology at its Indianapolis manufacturing plant.

Nemera Receives Drug Manufacturing Authorization for its Autoinjector Facility

September 28, 2017

Nemera is now authorized to handle, assemble, sterilize, and store pharmaceutical drugs and medicinal products for autoinjector combination products at its facility in Neuenburg, Germany.

Accelerating Genetic Medicine R&D Using Microfluidics

September 15, 2017

BioPharm International

This review examines how microfluidics has been used in the formulation, preclinical, and clinical development of gene-delivery nanoparticles.

FDA Grants Priority Review to Genentech’s Anti-Cancer Drug

August 28, 2017

Genentech gets priority review for its application seeking a new indication for its anti-cancer drug, Gazyva (obinutuzumab), in treating follicular lymphoma.

Alexion Gains Patent Protection Extension for Rare-Disease Drug

August 16, 2017

The US Patent and Trademark Office issued three new patents that extend protection for Alexion’s rare-disease drug, Soliris, for an additional 10 years.

Increasing Vial-to-Vial Homogeneity: An Analysis of Using Veriseq Nucleation on Production-Scale Freeze Dryers

December 01, 2016

BioPharm International

This report describes the first known attempt at quantifying the success of such processes in inducing nucleation on a 56–m2 freeze dryer operating at a load of 195,960 vials.

Nitto Avecia Expands Oligonucleotide Manufacturing Capacity

November 17, 2016

Avecia is adding drug substance capacity at its Milford, MA manufacturing site.

The Truth Behind Protein Aggregation in Prefilled Syringes

November 01, 2016

BioPharm International

Interactions between biologic drug products and the components of prefilled syringes can cause protein aggregation, but there are alternative materials that can help mitigate this problem.