Development

Agnes Shanley is senior editor of Pharmaceutical Technology.

Articles

As downstream bioprocessing improvements continue, efforts are underway to integrate downstream processes into continuous operations. 

Moving Closer to End-to-End Continuous Bioprocessing

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Connected, integrated bioprocessing enterprises with greater data analytics capabilities are coming.

Remote Monitoring and Big Data Advance Upstream Automation

Joshua Arias, joshua.arias@milliporesigma.com, is technical leader, BioReliance End to End Solutions, MilliporeSigma.

Mani Vinay Kumar Kotipalli is process engineer, Drug Substance Technology & Engineering, Amgen.

A unified scale-up approach, as presented here, can be applied to any unit operation.

A Unified Approach for Scaling Bioprocess Unit Operations

The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.

Cytiva Advances Fiber Chromatography Technology with New Launch

The new facility, to be located in Boston, MA, will contain experimental and analytical equipment for viral vector and advanced therapy process development and will expand the CDMO’s manufacturing capacity.

Fujifilm Corporation to Invest $40 Million into New Viral Vector and Advanced Therapy Facility

Feliza Mirasol is the science editor for 

Cell-culture optimization may see benefits from a synthetic biology-based approach that improves product titer, quality, and time.

Cultivating a Synthetic Biology-Based Approach to Improving Cell Culture

Thomas Prouzeau is a purification process development scientist at Sanofi.

Jerome Pezzini, Jerome.pezzini@sanofi.com, is purification process and technology leader at Sanofi.

Benoit Mothes is purification process development group head at Sanofi.

The development of an innovative purification process simplifies downstream processing for biologics.



EASY: a Disruptive mAb Purification Process to Reduce Cost of Goods

More collaboration and a knowledge-based approach, driven by better analytics and high-throughput system integration, are reducing the risk of failure.

Pinpointing Bioprocess Development Success

Toshihiko Otsubo is principal scientist of Biologics Process Development, 

Pharmaceutical Sciences, Takeda Pharmaceutical.

Shinji Tsuji is associate director at Biopharmaceuticals Process and Product Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Yoshiaki Miko is Associate Director of Biologics & New Modalities Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Tetsuya Moritake is associate director of Project Leadership & Operations, 

Pharmaceutical Sciences at Takeda Pharmaceutical.

director and head of Manufacturing Operations of Biogics Process Development

The increased use of single-use bags in biologic manufacturing poses the risk of pinholes and other defects that cannot currently be tested for.

Proposing a New Method of Detecting Pinholes in Single-Use 

The award will help a bioanalytics startup commercialize instrument technology for pharmaceutical antibody manufacturers.