Manufacturing, Cell Culture and Fermentation

Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow

July 01, 2020

Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.

Understanding Commercial Cell Culture Process Performance Variation Through Advanced Data Analytics

June 01, 2020

Advanced data analytics, including statistical modeling and machine learning technique, can enable more efficient and reliable bioprocesses.

Improving Upstream Predictability

March 02, 2020

Better understanding and control of cell behavior is yielding benefits, upstream and beyond.

The Future of Raw Material Sources for mAbs

March 02, 2020

The future of raw material sourcing for mAb production may lay in the sustainability of the source and the added benefits of newer technologies.

Cell Culture Variables for Gene Therapy Vectors

February 01, 2020

The production of viral vectors for use in gene therapy benefits from being able to use similar cell-culture processes as mAbs, but it faces limitations under current cell-culture technologies.

Single-Use Bioreactors: To Scale Up or Scale Out?

January 01, 2020

Industry experts debate the pros and cons of “going bigger” than the 2000-L industry norm in a single vessel.

The Evolving Role of Starting Materials in Cell and Gene Therapy

December 01, 2019

Accelerated approval pathways and growing demand for cell and gene therapies are putting pressure on providers of cellular starting materials, and they must ensure a steady supply.

Thermo Fisher Scientific to Invest $24 Million to Expand Global Bioproduction Capabilities

November 06, 2019

The company will invest $24 million into its Inchinnan, Scotland, site to expand global bioproduction capabilities with additional large-volume liquid manufacturing capacity for cell-culture media.

Making Biotech Training More ‘Hands On’

October 22, 2019

Ireland's National Institute of Bioprocessing Research and Training (NIBRT), together with technology providers such as GE Healthcare, and universities in Ireland and around the world, are developing courses that aim to close the gap between theoretical studies and practical workplace needs.

Turning to Plant Cell Culture for Sustainability

September 01, 2019

In an effort to secure a continuous, sustainable supply of an important vaccine ingredient, Agenus is turning to a plant cell-based cell culture method for production.