Elements of Biopharmaceutical Production

Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars

March 01, 2019

BioPharm International

A major advantage of SPR-based analysis is its ability to estimate the association and dissociation rate constants, an advancement over the traditional steady-state analysis of biomolecules.

Ending the Impasse on Drug Pricing

November 09, 2018

More-and earlier-interaction between R&D and payers will be essential if innovative therapies are to become more accessible for patients, and more profitable for manufacturers, said panelists at the 2018 Galien Foundation Forum.

Transcriptomics and the Production of Recombinant Therapeutics

June 01, 2018

BioPharm International

Transcriptomics plays a role in influencing the production of recombinant therapeutics in microbial and mammalian hosts.

Impact of Media Components on CQAs of Monoclonal Antibodies

September 01, 2017

BioPharm International

The authors review how media components modulate the quality of monoclonal antibody products

A Coiled Flow Inversion Reactor Enables Continuous Processing

December 01, 2016

BioPharm International

A novel coiled flow inversion reactor (CFIR) improves process productivity and performance.

Continuous Processing for the Production of Biopharmaceuticals

April 01, 2016

BioPharm International

The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platforms.

Antibody Production in Microbial Hosts

February 01, 2016

BioPharm International

The authors review the status of expression of antibodies in microbial hosts and present the recent advances in the production of aglycosylated antibodies in bacteria.

Use of Multivariate Data Analysis in Bioprocessing

April 06, 2015

BioPharm International

The authors review major developments in use of MVDA in bioprocessing applications.

Re-use of Protein A Resin: Fouling and Economics

March 01, 2015

BioPharm International

Large-scale implementation of Protein A chromatography offers several challenges.

Setting Standards for Biotech Therapeutics in India

November 01, 2014

BioPharm International

The authors take a look at the past and future impact of the Indian Pharmacopoeia Commission.