Whitepapers

Tumor-infiltrating lymphocytes may hold the key to treating solid tumors with cell therapies, and BioIVT’s DTC product line is a great source for TILs. In this white paper, you’ll read about defining what TILs are, their potential therapeutic applications, the characterization of BioIVT’s current donor pool by TIL content and the frequency of TILs by tumor tissue type.

When isolating peripheral blood mononuclear cells (PBMCs) from whole blood, red blood cell (RBC) contamination can have a significant impact on your downstream results. In this white paper, learn the sources of RBC contamination, the downstream impact of RBC contamination and mitigation strategies that will improve your results.

This article will discuss pharmaceutical package testing specifically Helium leak detection technology and how it solves cold supply chain challenges of today’s high-risk pharmaceutical products.  This article also addresses the importance of phase appropriate leak testing from manufacturing through product lifecycle.

Explore single-use bag system technologies for freeze/thaw applications in bulk drug substance (BDS) manufacturing. Transitioning to SUT can be an efficient, cost-effective option for biopharmaceutical manufacturers to hit performance targets.

Aggregates can affect the efficacy and safety of biologics. Few biophysical tools offer a combination of structural and functional assessment. Octet® systems can detect aggregates while monitoring functional activity at the formulation stage of drug development.

Eurofins’ whitepaper discusses insourcing & outsourcing solutions to solve the bio/pharma industry’s challenges with meeting drug development timelines and budgets with restricted headcounts.

Paper examines how cryogenic cold-temperature solutions are gaining favor versus traditional mechanical refrigeration methods in the manufacturing, storage, and distribution of vaccines due to their enhanced efficacy, stability and yield.

Used by leading pharma companies and CDMOs, the Beacon system offers an integrated end-to-end automated workflow for mammalian cell line development. Clones can be selectively enriched for unique phenotypes and multiple assays can be used to rapidly measure productivity of different antibody molecules.

This document outlines references to 21 CFR Part 11 and EudraLex Annex 11 and how they apply to the implementation of SoftMax Pro GxP Data Acquisition and Analysis Software in regulated environments.

This case study examines the benefits and challenges Nephron Pharmaceuticals Corporation faced integrating a STERIS VHP® Biodecontamination system into their high-volume compounding facility.

Learn about the use of the MAbPac RP capillary column for utmost sensitivity and excellent selectivity for the mass spectrometric analyses of intact proteins and mAb subunits.

The seasonal influenza vaccine market is projected to reach more than $4 Billion USD by the end of 2022. It is a safe assumption that as demand for seasonal influenza vaccines increases, so too with the demand for contract manufacturing organizations (CMOs) to support.

This application note demonstrates the DAR determination of brentuximab vedotin using HIC. Excellent reproducibility was found with the Agilent 1290 Infinity II Bio LC.