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Agilent
Articles
Addressing Regulatory Requirements for CRISPR sgRNA Purity with Orthogonal Chromatography
Webinar Date/Time: Session 1: Tue, Oct 22, 2024 11:00 AM EDT Session 2: Tue, Oct 22, 2024 2:00 PM EDT Session 3: Wed, Oct 23, 2024 2:00 PM JST
Robust Oligonucleotide Molecular Weight Confirmation by LC-MS
Webinar Date/Time: Tue, Oct 8, 2024 11:00 AM EDT
How to Achieve Confident Oligonucleotide Characterization and Purification
Discover how to accurately analyze purity and impurities, determine sequences, and more with next-generation technologies from Agilent.
Experiencing Bottlenecks in Your Raw Material ID?
Webinar Date/Time: Tuesday, January 9, 2024 at 11am EST | 8am PST | 4pm GMT| 5pm CET
Upgrading to Zero-Waste Raw Material Identification with the Agilent Vaya
Reaching sustainability and efficiency goals simultaneously is possible in RMID, a regulatory-enforced part of (bio)pharmaceutical drug manufacturing.
Best Practices for Analysis of In Vitro Transcribed (IVT) mRNA Using the Agilent Fragment Analyzer systems
This technical overview discusses best handling practices for IVT mRNA and analysis with the Fragment Analyzer systems, including sample handling and quantification tips.
Boost Productivity and Eliminate Waste in Raw Material ID
Webinar Date/Time: Thu, Aug 17, 2023 11:00 AM EDT
Oligo Workflow Resource Guide
End-to-End Workflow Solutions for Oligonucleotide Analysis - From research discovery to production QA/QC
End-to-End Oligonucleotide Solutions
This short video provides an overview of a complete, end-to-end oligonucleotide workflow solutions
MS1 Oligonucleotide Characterization Using LC/Q-TOF with HILIC Chromatography
In this application note, LC separation and MS1 mass identification of a variety of oligos without the use of ion‑pairing reagents is demonstrated. The LC separation allows subsequent positive mode use with little to no flushing or hardware changes. This HILIC-based method uses an Agilent InfintyLab Poroshell 120 HILIC-Z column and MS-friendly ammonium acetate-based mobile phases. The samples were analyzed on an Agilent 1290 Infinity II LC system and a 6545XT AdvanceBio quadrupole time-of-flight mass spectrometer (LC/Q-TOF).