Reliable Analysis of Antibody Drug Conjugates

This application note describes the drug-to-antibody determination of brentuximab vedotin using a ternary gradient with isopropanol as third channel organic modifier.

Process Analytical Technology (PAT): Online Monitoring and Control of Upstream Titer, Product Quality and Amino Acid Content Using 2D-LC with SegFlow Interface-Use Material Selection for Critical Storage Operations in Gene Therapy Development and Scale-up

*Europe Broadcast: Tuesday, May 18, 2021 9am EDT | 2pm BST | 3pm CEST and US Broadcast: Tuesday, May 18, 2021 2pm EDT | 1pm CDT | 11am PDT* Biopharmaceutical companies are transitioning from “quality-by-testing” philosophy to “quality-by-design” paradigms, and establishing QbD-based PAT tools to increase product and process understanding. Due to the deficit of analytical methods to support QbD-driven continuous bioprocessing, biopharmaceutical companies are actively developing PAT tools to comply with QbD regulations. *On Demand Until May 18, 2022*

LC-MS Analysis of Adeno-Associated Virus Critical Quality Attributes

*Tuesday, May 11, 2021 at 9am EDT | 2pm BST | 3pm CEST, Tuesday, May 11, 2021 at 2pm EDT | 1pm CDT | 11am PDT* Adeno-associated viruses (AAVs) are an important tool enabling the delivery of next-generation gene therapies. *Available On Demand Until May 11, 2022*