Efficient virus recovery and impurity removal are challenges for purification of viruses such as H1N1. In a single purification step, Nuvia HP-Q AEX Resin resulted in excellent recovery and impurity removal.
Traditional sequential chromatography usually requires user manipulation which may hinder reproducibility in protein purification runs. Multidimensional chromatography improves the process without sacrificing efficacy. This study compares both purification workflows demonstrating equivalent purity.