Whitepapers

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS

The paper reviews a new 24-well filter plate that clarifies and sterile filters high-density cells in one step in minutes. Its depth filter efficiently clarifies cells while a dual-layer membrane provides high-performance sterile filtration

This application note demonstrates the importance of using orthogonal mass spectrometry techniques for primary sequence identification of monoclonal antibodies.

This application note shows the combination of mAb titer determination and spent media analysis on a bio-inert LC system with MS/UV detection during a CHO bioprocess.

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS

This white paper examines better solutions for flexible biopharmaceutical production sites and process designs that meet the needs that outdated traditional cleanroom facility and infrastructures can no longer provide.

An effective, high recovery method for purification of a DMT-on oligonucleotide and the removal of a DMT-group from an oligonucleotide in a single HIC purification step is described.

This application note demonstrates how Native SEC-MS offers simpler and faster analysis with no sample preparation, and how to achieve 5-fold throughput gains for lead selection studies using a dual LC system.

Discover how platforms drive efficiency and get products to market faster. See why data connectivity improves quality and leads to better outcomes. Learn how to transform quality from an obligation to a business accelerator

Recombinant mAbs tend to be unstable and susceptible to modification/degradation. These mAbs need to be identified/monitored for successful drug development. New advanced LC–MS workflows have been developed to meet such needs.

AAE and MS integration enables comprehensive HCP analysis, facilitates process development, and helps determine whether your HCP ELISA is fit for purpose of process monitoring and product lot release.