Tosoh Bioscience LLC

Articles

Tosoh 2 Step mAb Purification Platform

Combining high performance protein A capturing and a single polishing step on a salt-tolerant anion exchange resin, downstream costs were reduced by 45% in this Tosoh 2-step process for mAb purification.

Capture of a scFv from E.coli 

Method for capture of scFV and post-capture-washing condition with chaotropic agents is described. The post-capture washing condition significantly improved HCP removal to increase scFV purity.

Protein A Resin to Reduce Production Cost

This report details how using high capacity TOYOPEARL AF-rProtein A HC-650F resin will reduce production costs, on a per-gram produced basis.

FcR Affinity Chromatography of a Therapeutic Antibody

This application note demonstrates that the TSKgel® FcR-IIIA-NPR affinity column provides fast assessment of biologic activity and glycoform patterns of antibodies.