Whitepapers

This paper summarizes approaches for modulating antibody effector functions and pharmacokinetics, and provides examples of antibodies in clinical studies employing such approaches.

Combining high performance protein A capturing and a single polishing step on a salt-tolerant anion exchange resin, downstream costs were reduced by 45% in this Tosoh 2-step process for mAb purification.

This application note demonstrates the importance of using orthogonal mass spectrometry techniques for primary sequence identification of monoclonal antibodies.

Growing trends in oligonucleotide and gene therapy development Commentary on the current global and regional market landscapes The latest methods for the advancement of oligonucleotide and gene therapies and much more!

Preventing contamination in pipetting is paramount to achieving reliable results. It requires identification of the potential contamination mechanisms in order that they can all be addressed.

Multiple separation steps are often required to eliminate product- and process-related impurities impacting biopharmaceuticals. This study shows that buffer composition has an effect on target purity and recovery when using Nuvia aPrime 4A, a mixed-mode resin.

This new white paper from Brooks Instrument describes the inner workings of digital MFCs and their ability to gather, generate and communicate a range of process data. The content reviews ways to utilize MFC device data to improve process control, system uptime, diagnostics, preventive maintenance and bioprocessing yields.

2020’s Pharma Manufacturing Trends The world of pharmaceutical manufacturing is changing fast Learn how today’s top pharmaceutical manufacturers are innovating

-The MYCAP CCX system removes the need to perform transfers in a biosafety cabinet -Reduces the risk of contamination by eliminating significant nonaseptic procedures

To ensure that no contaminating or hazardous residual components remain after protein purification during biologic development, additional sanitization steps may be required for the instrumentation utilized during these processes.

This new white paper from Brooks Instrument describes the inner workings of digital MFCs and their ability to gather, generate and communicate a range of process data. The content reviews ways to utilize MFC device data to improve process control, system uptime, diagnostics, preventive maintenance and bioprocessing yields.

Lunatic pushes the rock-solid quantification technique of UV/Vis spectrophotometry to the next level of accuracy and throughput with state-of-the-art optics, precision microfluidics, honed signal processing, and purpose-built applications.