The authors describe a new assembly for bulk and final drug product filling operations.
Upstream Processing
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The Making of mRNA
A tidal wave of questions floats the need for more upstream automation.
Milestone Approval to Steady Stream, Gene Editing Revs Up
The milestone approval of a gene-edited therapeutic paves the way for gene-editing technologies.
The Pros and Cons of Adherent Versus Suspension Cell Culture
Both adherent and suspension cell culture approaches have their pros and cons, which must be considered for process development.
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BioPharm talks with Tarja Mottram, CEO of Action for Results, about key business considerations when starting out.
Demonstration of large-scale stem-cell scale-up.
Recombinant albumin can stabilize a drug product and assist in API release.
Key technical considerations when developing a clinical project in the biotech world.
This month, we revisit "Industrial-Scale Mammalian Cell Culture, Part I: Bioreactor Design Considerations."
Recombinant technology can be used to produce conjugate vaccines.
Readers react to the economic turmoil of the past year and look longingly forward to 2012.
New technology is designed to improve production efficiency by taking advantage of the properties of single-use bags.
Biosimilar manufacturers need better expression systems and analytical tools to compete.
Despite their difficult approval pathway, biobetters offer the potential for innovation and decreased healthcare costs.
An evaluation of the technologies needed to develop a safe, effective, and economically efficient vaccine. This article is part of a special section on vaccines.
Development of the ideal DNA vaccine requires the optimization of delivery strategies and plasmid vectors.
A survey provides insight into drug companies' plans for spending on outsourced services. This article contains bonus online material.
The authors provide insight into microRNA biology, and the simplicity of anti-miR oligonucleotide drug delivery.
How to strike a balance between site autonomy and global coordination.
The authors describe challenges faced in transfer and scale-up of a fermentation process.
Cell concentrations and resulting protein concentrations are higher in a concentrated fed-batch process than in a standard fed-batch culture system.
A recent industry survey shows keen interest in improving bioreactors and cell-culture media.
An overview of applications in the analysis of nutrients and metabolites.
A plant-based expression system could provide greater speed and capacity at a comparatively low cost.
A hollow fiber matrix allows for efficient harvest of secreted proteins.
The authors discuss an alternative to traditional Protein A resins.
The authors developed a test for defects in filter membranes.
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