Upstream Processing

Latest News

April 1st 2005

Developing the Future: Big Questions, Multiple Answers

When you don't know the answer to a question, ask an expert. If the question is really big, ask more experts. If you have a collection of difficult questions, run a poll of many experts. That, in effect, was the impetus for Eden Biodesign to survey 670 BioPharm International subscribers with questions as to what will be the development mechanism to achieve safe, effective, and cheap new medicines.

The Making of mRNA

A tidal wave of questions floats the need for more upstream automation.

Milestone Approval to Steady Stream, Gene Editing Revs Up

The milestone approval of a gene-edited therapeutic paves the way for gene-editing technologies.

The Pros and Cons of Adherent Versus Suspension Cell Culture

Both adherent and suspension cell culture approaches have their pros and cons, which must be considered for process development.

Managing the Transition from Research to Development: Implementation of a Manufacturing Strategy

January 1st 2005

In order to institute a GxP mindset across the organization, support and respect for quality systems should come from the top down.

NASA's Cell Culture Unit Brings Space Station Research Down to Earth

ByDonald Vandendriesch,Liping Sun, Ph.D

April 5th 2004

A profusion of present-day bioreactor and fermentor systems offers remarkably diverse capabilities, ranging from microfluidics to bulk production vats, simple petri dishes to complex artificial organ cultivators, and suspension, adhesion, perfusion, and many other culture management methods. Each of these systems is well suited to address specific research problems, but few are widely adaptable to diverse experiment demands - such as those conducted in space.