Manufacturing

Articles

Cytiva’s new facility in Shrewsbury, MA will make equipment such as single-use bioreactors. 


Cytiva Opens New Manufacturing Facility in Massachusetts

Cytiva is adding process development, media and assay development, and contract development services at its facilities in Korea, Japan, Sweden, and the UK.

Cytiva Expands Cell and Gene Therapy Fast Trak Services

Set to be operational by the first quarter of 2022, the 140,000-ft2 facility will feature up to six 2000-L, single-use bioreactor systems along with additional harvest and purification equipment to produce up to 100 commercial batches annually. 

KBI Biopharma to Open $150 Million Commercial Manufacturing Facility in North Carolina

Biopharma can apply new manufacturing practices adopted during the COVID-19 pandemic to enhance bioprocessing.

Pandemic Response Lessons for Biopharma Companies

The latest advances in downstream technologies include sterile disconnects for single-use manufacturing systems, ligand technologies for purifying RNA and for COVID-19 vaccines, and an automated perfusion system.

What’s New in Downstream Technologies 

The new facility at the company’s San Diego, CA, site will be for late phase and commercial CGMP manufacturing.

Abzena Invests in New $60-Million CGMP Manufacturing Facility

The investment will include new manufacturing lines and increased automation to deliver additional manufacturing capacity.

Cytiva Invests $500 Million Over 5 years to Expand Global Capacity

Toshihiko Otsubo is principal scientist of Biologics Process Development, 

Pharmaceutical Sciences, Takeda Pharmaceutical.

Shinji Tsuji is associate director at Biopharmaceuticals Process and Product Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Yoshiaki Miko is Associate Director of Biologics & New Modalities Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Tetsuya Moritake is associate director of Project Leadership & Operations, 

Pharmaceutical Sciences at Takeda Pharmaceutical.

director and head of Manufacturing Operations of Biogics Process Development

The increased use of single-use bags in biologic manufacturing poses the risk of pinholes and other defects that cannot currently be tested for.

Proposing a New Method of Detecting Pinholes in Single-Use 

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Facility and equipment design are important, but the team and its experience matter most.

Strategizing for Rapid Changeovers in Biologics Manufacturing

New therapeutics modalities and the need for greater process efficiency are driving technology development.

Chromatographic Science Clarifies Separation Challenges

Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.

Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow

The new facility in County Mayo includes an ISO class 7 cleanroom for the manufacturing of single-use systems.


Meissner Opens New Manufacturing Facility in Ireland

The ASTM standard describes how to evaluate single-use systems for foreign particle analysis. 

New ASTM Standard Addresses Foreign Particles in Biomanufacturing Processes

Jennifer Markarian is manufacturing editor of BioPharm International.

Pumps and other components meet the demands of single-use systems in biopharmaceutical downstream processing.

Fluid Handling Considerations

Editor of Pharmaceutical Technology Europe

Single-use solutions continue to grow in popularity, largely as a result of the cost and time efficiencies they can afford biopharma companies.


Seeing Success with Single-Use Solutions

The new BIOSTAT STR Generation 3 with BIOBRAIN bioproduction platform offers process intensification with automated feed and bleed and integrated cell retention functionality.

Sartorius Launches New Automated Single-Use Bioproduction Platform

The expansion gives the company diversified capacity running cell production lines featuring Sartorius-brand 2000-L disposable bioreactors and now GE-brand 2000-L single-use bioreactors.

MabPlex Launches New 2000-L Cell Culture Production Lines

GE Healthcare Life Sciences’ new facility for cell and gene processing supplies will be open in 2022. 

GE Builds Single-Use Kit Manufacturing Facility in Switzerland

Feliza Mirasol is the science editor for 

Industry experts debate the pros and cons of “going bigger” than the 2000-L industry norm in a single vessel.

Single-Use Bioreactors: To Scale Up or Scale Out?

The latest advances in upstream technologies include single-use equipment and a protein analyzer for titer monitoring, as well as new plasmid DNA manufacturing capability. 

Manufacturing Systems, Single-Use