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Manufacturing, Monoclonal Antibodies

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February 2nd 2007
ALTERNATIVES TO PROTEIN A: Improved Downstream Process Design for Human Monoclonal Antibody Production

Affinity purification schemes for antibody production have certain limitations keeping up with cell culture expression levels as they reach and exceed 10 g/L. New downstream purification processes are based on low cost, long lasting, and high binding (40–100 mg/mL) cation exchange resins.

January 1st 2007

Downstream Processing: A Revalidation Study of Viral Clearance in the Purification of Monoclonal Antibody CB.Hep-1

June 2nd 2006

Technical and Economical Evaluation of Downstream Processing Options for Monoclonal Antibody (Mab) Production

April 1st 2006

Cleaning Polyethersulfone Membranes After Ultrafiltration-Diafiltration in Monoclonal Antibody Production

February 1st 2006

GMP Compliance for Production of CB.Hep-1 Monoclonal Antibody as a Biological Reagent