Senior Director of Process Development at Medarex

Alahari Arunakumari, PhD

Articles

Precipitation prior to capture chromatography offers a simple, robust, and economical method to remove CHO host cell proteins and DNA.

Precipitation of Process-Derived Impurities in Non-Protein A Purification Schemes for Antibodies

ACF medium sped up cell-line development.

The Impact of Cell Culture Medium on Cell Line and Process Development Timelines and Strategies

In three non-affinity purification processes based on cation exchange capture with high binding capacity, applying a host cell protein exclusion strategy enabled robust scale up and better economics.

Advances in Non-Protein A Purification Processes for Human Monoclonal Antibodies

An alternative approach to traditional Protein A schemes is comparable in overall efficiency, product recovery, and quality.

Author | Alahari Arunakumari, PhD