Jue (Michelle) Wang, PhD


New Jersey

Jue (Michelle) Wang, PhD, is assistant director, purification process development, at Medarex Inc.


ALTERNATIVES TO PROTEIN A: Improved Downstream Process Design for Human Monoclonal Antibody Production

Affinity purification schemes for antibody production have certain limitations keeping up with cell culture expression levels as they reach and exceed 10 g/L. New downstream purification processes are based on low cost, long lasting, and high binding (40–100 mg/mL) cation exchange resins.