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Downstream Processing|

Upstream Processing

Alessandro Pieri

Alessandro Pieri, PhD, is scientific leader & GSK associate fellow at GSK, Italy

Articles by Alessandro Pieri

Computational Chemistry - Conceptual Illustration | Image Credit: © ArtemisDiana - © ArtemisDiana - stock.adobe.com

Purification of Protein by HIC: Mechanistic Modeling for Improved Understanding and Process Optimization

ByLucrèce Nicoud,Yohann Le Guennec ,Edouard Nicoud ,Antonio Cardillo,Elena Lietta,Elisa Innocenti ,Alessandro Pieri

April 1st 2023

In this article, a simple chromatographic model is proposed that is capable of predicting the impact of pH and ionic strength on HIC chromatograms.

Latest Updated Articles

Purification of Protein by HIC: Mechanistic Modeling for Improved Understanding and Process Optimization
April 1st 2023