Antibody therapeutics are the largest class of biotherapeutics. Over the years, development beyond traditional monoclonal antibodies (mAbs) has increased. Today, we see multispecific and bispecific antibodies, antibody fragments, and antibody drug conjugates in the development pipeline. Manufacturing platform approaches conveniently used for many traditional mAbs are being adopted or tweaked to fit the respective molecule. In this ebook, you will learn about considerations and tips for developing chromatography protocols for antibody variants.
This white paper summarizes information around chromatography resin variability, providing support for developing robust purification bioprocesses.
This white paper summarizes information around chromatography resin variability, providing support for developing robust purification bioprocesses.
Give a quick overview of the oligonucleotide market, what is happening. Cover the typical challenges with oligonucleotide synthesis in the process development phase and solutions for those. Key considerations when scaling up oligonucleotide synthesis
Innovation has brought about a diversification of therapeutics molecules. In this discovery interview we will explore what mechanistic modelling is and how you can use it to develop these diverse therapeutics and what challenges this brings to the future of your process development.
Cytiva experts answer your top questions about challenging host cell protein assays to improve risk mitigation.