Modular Bioreactor Simplifies Process Development

July 1, 2016

BioPharm International

Volume 29, Issue 7

Page Number: 49

The ambr 250 mini benchtop bioreactor system from Sartorius Stedim Biotech can be used for parallel fermentation and cell culture.

The ambr 250 mini benchtop bioreactor system from Sartorius Stedim Biotech can be used for parallel fermentation and cell culture. The system combines a unique single-use bioreactor vessel and expandable system design for process development. The new ambr 250 modular system consists of a workstation with two, four, six, or eight single-use bioreactors, with a working volume range of 100-250 mL. These mini bioreactors, based on the same stirred tank bioreactors in the high throughput system, contain impellers suitable for fermentation or cell culture, and scale up to larger bioreactors. They are also fully integrated with liquid reservoirs and syringe pumps, allowing rapid experimental set up and turn around, thus significantly increasing lab efficiency. Once installed, the bioreactor has all the required process services for parameter control, including pH, DO, temperature, and agitation. Feeds can also be delivered from the reagent reservoirs via syringe pumps into the bioreactor. One control unit is capable of controlling up to eight bioreactor stations independently using a touch screen user interface.

Sartorius Stedim Biotech