Whitepapers

By using optimized reagents and method conditions, learn how to reduce 2-AB labelling of glycans from days to just two hours.

Discover how LC/MS peptide mapping can be used to characterize and quantify different monoclonal antibody (mAb) critical quality attributes (CQAs).

Small interfering RNAs (siRNAs) are a promising type of RNA-based therapeutic drugs that demonstrate effectiveness on gene silencing through RNA interference (RNAi).

Workflow for the characterization of critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with identification of the capsid proteins.

Learn how to perform method optimization using a bio-inert quaternary LC instrument to screen multiple mobile phase compositions for aggregate analysis of NIST mAb.

How to use of size exclusion chromatography (SEC) and hydrophobic interaction chromatography (HIC) for the analysis of camelid single-domain antibodies (nanobodies).

This Application Note describes the preparation and analysis of released N-glycans from biotherapeutic glycoproteins using InstantPC and 2-aminobenzamide (2-AB) labels.

Monitoring and controlling your bioprocess just got easier with simplified sample loading. Watch Ryan Lybarger, Senior Field Application Consultant, demonstrate how to analyze substrates, metabolites, product titer, and more.

Cerba Research initiated custom kit building and distribution for an infectious disease study, during the COVID-19 pandemic, in 10 days. A typical timeline is 8 weeks.

This case study will examine the subject of single-use plastics used in biopharmaceutical manufacturing and extractables & leachables from the perspective of the contract research organization.

For immuno-oncology trials, partner with a global central lab that can generate early insights to optimize your protocol and ramp up to commercial scale while preserving budgets and timelines.

A frozen shipping study conducted on single-use fluoropolymer bags following new guidelines that help to mitigate the risks during frozen shipping while ensuring consistent product quality in cold chain distribution.

Method for capture of scFV and post-capture-washing condition with chaotropic agents is described. The post-capture washing condition significantly improved HCP removal to increase scFV purity.

Glycosylation homogeneity and pattern can be increase with cell line engineering and bioprocess optimization. But, these can be time-consuming and might compromise yield. In vitro glycoengineering can solve these problems and is independent from the cell line and the bioprocess used.

Despite exhausting all disinfection methods after resuming operations this year, this international biologics provider repeatedly failed Environmental Monitoring test standards, delaying $5M in product release. See how Bioquell’s Rapid Bio Decontamination Service provided a fast, effective solution.

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS