Featured Resources for Glycan Analysis
N-Glycan Analysis: Better Together
In this brochure, you will learn about Agilent solutions for sample preparation for N-glycans to support your LC/FLD/MS and CE workflows.
Development of a Rapid 2-AB Sample Preparation Workflow for N-Glycan Release and Labeling
In this application note, we will present the development and application of a rapid N-glycan sample preparation workflow using a five-minute in solution deglycosylation step followed by direct on-matrix 2-AB labeling and cleanup. Without the need for a dry down step, samples are ready for analysis in approximately 2 hours.
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Profiling Glycosylation of Monoclonal Antibodies at Three Levels Using the Agilent 6545XT AdvanceBio LC/Q-TOF
Access this application note to discover how our Q-TOF LC/MS solutions can help you in the analysis of glycoforms on the intact and reduced mAbs molecules as well as in the analysis of released glycan.
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Glycopeptide Characterization for Various Monoclonal Antibodies Using the Agilent 6545XT AdvanceBio LC/Q-TOF
In this application note, you will learn about glycopeptide analysis. This workflow shows results not only in glycan-relative quantitation, but also N-glycosylation site(s) information.
The Role of Forced Degradation in Method Development, Manufacturability, and CMC Strategy
April 28th 2025Forced degradation studies are critical in biologics development, particularly for monoclonal antibodies (mAbs). These studies simulate long-term environmental stressors to uncover degradation pathways and ensure the stability of critical quality attributes (CQAs), aiding in robust chemistry, manufacturing, and controls (CMC) strategies and regulatory compliance.
Filter Sizing for Process Optimization in Life Sciences Sterile Filtration
April 24th 2025Bench-scale filterability studies play a critical role in optimizing sterile filtration in biopharmaceutical manufacturing. By guiding the selection and sizing of filters, these studies help streamline processes, improve scalability, and reduce costs. Through data-driven case studies, this paper highlights how the strategic use of pre-filters and membrane materials can maximize throughput and minimize filter fouling.
Ensuring Biologic Stability with Tailored and Cutting-Edge Lyophilization Solutions
April 14th 2025Explore how tailored lyophilization solutions, integrated with quality-by- design principles and advanced modeling, help optimize stability, reduce costs, and enhance global accessibility for biopharmaceuticals.
Top 10 Cleanroom Problems That Can Be Prevented via Preventative Maintenance
April 14th 2025Cleanrooms require strict environmental control to maintain sterility, prevent contamination, and ensure seamless operations. Without a proactive preventative maintenance (PM) program, various issues can arise, leading to costly downtime, contamination risks, and operational inefficiencies. Below are ten common cleanroom problems that can be effectively mitigated through proper PM practices.
