Articles by Agilent Technologies

This technical overview compares the characterization of NISTmAb using the ProteoAnalyzer with published NIST data obtained via traditional single capillary CE-SDS technology. The results show strong correlation with the reference data, confirming that the ProteoAnalyzer is a reliable tool for analytical workflows.

Time to results can be significantly reduced with the use of RapidFire high-throughput mass spectrometry (MS). With this technique, a lab’s next great innovation can be brought from conception to reality in a timely and efficient manner.

This application note presents a side-by-side comparison of the AdvanceBio and GlycoWorks kits for the preparation and analysis of released N-glycans.

This application note presents a side-by-side comparison of the AdvanceBio and GlycoWorks kits for the preparation and analysis of released N-glycans.

Webinar Date/Time: Monday, March 20th, 2023 at 11am EDT|8am PDT|3pm GMT|4pm CET

This Application Note presents streamlined workflows for preparation of InstantPC and 2-AB labeled N-glycans coupled with analysis using Agilent LC/FLD/MS.


This Application Note presents streamlined workflows for preparation of InstantPC and 2-AB labeled N-glycans coupled with analysis using Agilent LC/FLD/MS.









By using optimized reagents and method conditions, learn how to reduce 2-AB labelling of glycans from days to just two hours.

Discover how LC/MS peptide mapping can be used to characterize and quantify different monoclonal antibody (mAb) critical quality attributes (CQAs).

Small interfering RNAs (siRNAs) are a promising type of RNA-based therapeutic drugs that demonstrate effectiveness on gene silencing through RNA interference (RNAi).

Workflow for the characterization of critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with identification of the capsid proteins.

Learn how to perform method optimization using a bio-inert quaternary LC instrument to screen multiple mobile phase compositions for aggregate analysis of NIST mAb.

How to use of size exclusion chromatography (SEC) and hydrophobic interaction chromatography (HIC) for the analysis of camelid single-domain antibodies (nanobodies).

This Application Note describes the preparation and analysis of released N-glycans from biotherapeutic glycoproteins using InstantPC and 2-aminobenzamide (2-AB) labels.

*** Two Live Events! Monday, Oct. 26, 2020 at 9am EDT| 1pm GMT| 2pm CET and Monday, Oct. 26, 2020 at 2pm EDT| 1pm CDT| 11am PDT*** Join us for this web seminar to learn about the utility of mass spectrometry for characterizing adeno-associated viruses (AAVs), including how intact mass spectrometry can accurately confirm AAV capsid proteins, how AAV post-translational modifications can be identified and confirmed, and how upfront sample preparation can improve mass spec accuracy and resolution. ***On demand available after final airing until Oct. 26, 2021***