Capillary Electrophoresis System Optimizes IgG Purity Analysis
The advanced capillary electrophoresis system, Maurice, from ProteinSimple is used for the quantitative analysis of identity, purity, and heterogeneity profiles of biopharmaceuticals.
The advanced capillary electrophoresis system, Maurice, from ProteinSimple is used for the quantitative analysis of identity, purity, and heterogeneity profiles of biopharmaceuticals. The system includes a native fluorescence detection mode, capability for size-based separation across a broad range of molecules, and offers optimized methods for IgG purity analysis. Maurice includes a cartridge for each application, which allows researchers to swap between applications without cleanup steps or a risk of cross-contamination. The platform includes three systems: Maurice C. for quantitative pI and Charge heterogeneity analysis, Maurice S. for IgG purity analysis by CE-SDS, and Maurice which completes both applications.
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Mechanistic Hypothesis of Toxicity: Driving Decision Making in Preclinical Translation
July 16th 2025Mechanistic toxicity hypothesis is essential in guiding decision-making and predicting toxicities during the preclinical stages of drug development. The authors highlight the growing importance of integrating advanced technologies like mass spectrometry imaging into toxicology to enhance preclinical translation, foster innovation in therapeutic development, and ultimately improve drug safety and efficacy.
