Whitepapers

A frozen shipping study conducted on single-use fluoropolymer bags following new guidelines that help to mitigate the risks during frozen shipping while ensuring consistent product quality in cold chain distribution.

Method for capture of scFV and post-capture-washing condition with chaotropic agents is described. The post-capture washing condition significantly improved HCP removal to increase scFV purity.

Glycosylation homogeneity and pattern can be increase with cell line engineering and bioprocess optimization. But, these can be time-consuming and might compromise yield. In vitro glycoengineering can solve these problems and is independent from the cell line and the bioprocess used.

Despite exhausting all disinfection methods after resuming operations this year, this international biologics provider repeatedly failed Environmental Monitoring test standards, delaying $5M in product release. See how Bioquell’s Rapid Bio Decontamination Service provided a fast, effective solution.

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS

This application note collection will help ensure you have the right tools to succeed in the biopharmaceutical environment, from research and process development to quality control.

Digital transformation in pharma is not just about going paperless. It’s using technology and data to build a scientific and business ecosystem, reducing risk, accelerating innovation, and driving growth.

Routine Environmental Monitoring in GMP cleanrooms is a manual process and can be complex, involving thousands of sample data points per month, manual data transcription and all too frequently data gaps and integrity challenges. This paper shows how the new MET ONE 3400+ non-viable air particle counter from Beckman Coulter Life Sciences can be automated to help manage these challenges.

Transmissible diseases are no longer scarce and geographically limited, but are becoming a frequent occurrence. To prevent the spread of outbreaks, detection and containment are the first line of defense.

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS

The paper reviews a new 24-well filter plate that clarifies and sterile filters high-density cells in one step in minutes. Its depth filter efficiently clarifies cells while a dual-layer membrane provides high-performance sterile filtration

This application note demonstrates the importance of using orthogonal mass spectrometry techniques for primary sequence identification of monoclonal antibodies.

This application note shows the combination of mAb titer determination and spent media analysis on a bio-inert LC system with MS/UV detection during a CHO bioprocess.

Bridging Anti-CHO HCP Antibodies from Two 3rd Generation Cygnus CHO HCP ELISA Kits by AAE-MS

This white paper examines better solutions for flexible biopharmaceutical production sites and process designs that meet the needs that outdated traditional cleanroom facility and infrastructures can no longer provide.

An effective, high recovery method for purification of a DMT-on oligonucleotide and the removal of a DMT-group from an oligonucleotide in a single HIC purification step is described.