Whitepapers

Efficient virus recovery and impurity removal are challenges for purification of viruses such as H1N1. In a single purification step, Nuvia HP-Q AEX Resin resulted in excellent recovery and impurity removal.

Traditional sequential chromatography usually requires user manipulation which may hinder reproducibility in protein purification runs. Multidimensional chromatography improves the process without sacrificing efficacy. This study compares both purification workflows demonstrating equivalent purity.

Roche Pharma Research and Early Development lab automation specialist, Pawel Linke, discusses their approach to doubling the number of projects in process development without significantly increasing headcount.

The traditional packaging for frozen BDS applications has significant weaknesses at lower temperatures.  This paper discusses new materials and freeze-thaw systems to meet these challenges.

Glycosylation homogeneity and pattern can be increase with cell line engineering and bioprocess optimization. But, these can be time-consuming and might compromise yield. In vitro glycoengineering can solve these problems and is independent from the cell line and the bioprocess used.