
- BioPharm International-04-01-2014
- Volume 27
- Issue 4
High-Performance Separation-Electrospray Ionization System
High-Performance Separation-Electrospray Ionization System
AB Sciex introduces the CESI 8000 System for Biologics Characterization, a high-performance separation-electrospray ionization system for mass spectrometry. CESI combines capillary electrophoresis (CE) and electrospray ionization (CESI). This new front-end CESI technology from the company’s SCIEX Separations business can be integrated with the AB Sciex TripleTOF 5600+ MS system.
The CESI 8000 provides improved results compared to dual-method liquid chromatography/mass spectrometry-based approaches. From a single digest and run, users of CESI-MS gain identity and purity information with 100% coverage in a peptide map, heterogeneity information with ultrasensitive glycopeptide quantitation, and stability information identifying, deamidation, cyclization, and oxidation.
According to the company, CESI technology is designed to improve biophysicochemical characterization and guide the development of biologics-based therapeutics. Specifically, CESI-MS serves to improve ionization efficiency and reduce ion suppression.
Articles in this issue
over 11 years ago
Line of Environmental Measurement Productsover 11 years ago
UPLC Separation Intergrates into Mass Spectrometersover 11 years ago
FDA and Manufacturers Seek a More Secure Drug Supply Chainover 11 years ago
Biotech IPOs on a Hot Streakover 11 years ago
Global Instability Affects the Pharma Market in Brazilover 11 years ago
Raw Material Variabilityover 11 years ago
Monoclonal Antibodies Key to Unlocking the Biosimilars Marketover 11 years ago
Publishing Beyond the Printed Pageover 11 years ago
Biopharma Outsourcing Activities UpdateNewsletter
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