Core-Shell Phase Column Increases Reproducibility

April 1, 2015
BioPharm International, BioPharm International-04-01-2015, Volume 28, Issue 4

Phenomenex’s Kinetex F5 is a pentafluorophenyl propyl core-shell phase column designed to improve reproducibility and reduce method development time.

 

Phenomenex’s Kinetex F5 is a pentafluorophenyl propyl core-shell phase column designed to improve reproducibility and reduce method development time. A combination of polar and non-polar interactions including hydrogen bonding, electrostatic, hydrophobic, aromatic, and steric/planar mechanisms makes the column useful for high performance liquid chromatography (HPLC)/ultra high performance liquid chromatography (UHPLC) development work. The column allows for reversed phase, 2D-LC, hydrophilic interaction liquid chromatography, supercritical fluid chromatography, or 100% aqueous separation modes, while the fluorinated groups and carbon ring structure are ideal for methods that include halogenated, conjugated, or isomeric compounds.

The column is available in 2.6 and 1.7 μm particle sizes. The 2.6 μm version provides comparable performace to sub-2 μm particles for HPLC and UHPLC systems. The 1.7 μm column delivers 20% greater efficiency than fully-porous sub-2 μm products.

Phenomenex