Webinar Date/Time: Tue, Dec 3, 2024 Session 1: 9:00 am EST | 1:00pm GMT | 2:00pm CST Session 2: 2:00 pm EST| 1:00pm CST| 11am PST
Multi-column chromatography (MCC) has gained popularity for monoclonal antibody (mAb) capture processes, potentially offering benefits of higher productivity and lower resource consumption, including buffers and resin. However, there is still a need to demonstrate the efffectiveness of polishing steps using MCC. This study will do just that by demonstrating the implementation of step gradients for mAb polishing using a MMC system and technique.
Register Free: https://www.biopharminternational.com/bp_w/mAb-polishing
Event Overview:
Monoclonal antibodies (mAbs) are essential biopharmaceuticals due to their specificity and targeted therapeutic potential. Recent shifts in mAb production favor continuous over batch processes, yet downstream processing remains a costly bottleneck. Multi-column chromatography (MCC), including continuous capture and simulated moving bed (SMB) chromatography, offer cost-effective alternatives with higher productivity and lower resource consumption. This study demonstrates the implementation of step gradients for mAb polishing, further extending the use-case spectrum of SMB technology in biopharmaceutical manufacturing.
Key Learning Objectives:
Who Should Attend:
Speakers:
Marissa Heino
Product Specialist, Multi-Column Chromatograhy
Tosoh Bioscience
Marissa Heino joined Tosoh Bioscience at the start of 2024 as a product specialist for the Octave Multi-Column Chromatography (MCC) product line. Marissa's work revolves around developing a deep understanding of MCC technology offered by Tosoh Bioscience to educate customers and aid in the transition to MCC and continuous manufacturing.
Carsten-René Arlt, PhD
Application Scientist, Process Instruments
Tosoh Bioscience
Carsten-René Arlt earned his PhD in the development of new chromatographic modes and their transition to continuous MCC. Joining Tosoh Bioscience in 2021, he focused further on problem solving skills for multi-column processes as an application scientist.
Register Free: https://www.biopharminternational.com/bp_w/mAb-polishing
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