Complementary mAb Polishing Solutions for Viral Clearance and Aggregate Removal

Removing viruses and aggregates during mAb polishing remains a key challenge for ensuring product quality and regulatory compliance. Join this webinar to explore case studies demonstrating how HIC and CEX resins enable effective viral clearance and aggregate removal in downstream purification.

Register Free: https://www.biopharminternational.com/bp_w/mAB-Polishing-Solutions

Event Overview:

Monoclonal antibody polishing remains a critical challenge in downstream bioprocessing, where effective removal of viruses and aggregates is essential for product quality, patient safety, and regulatory compliance. ICH Q5A(R2) guidelines require manufacturers to demonstrate robust viral clearance, while residual aggregates can increase immunogenicity risk and reduce therapeutic potency. This presentation explores chromatographic strategies for addressing these purification challenges, highlighting approaches for both virus removal and aggregate reduction during mAb polishing. Through 2 case studies, attendees will gain insight into practical methods for improving impurity clearance and achieving high-purity monoclonal antibody products.

Key Learning Objectives:

• Learn about viral and aggregate removal techniques during mAb development.
• Discover how to streamline mAb polishing with HIC and CEX resins.
• Gain further understanding of the antibody purification process.

Who Should Attend:

• Downstream Process Development Scientists
• Process Engineers
• MSAT Scientists

Speaker:

Yuliya McAnany, MS
Applications Scientist – Process Resins
Tosoh Bioscience LLC

Yuliya McAnany is an applications scientist – process resins at Tosoh Bioscience in King of Prussia, Pennsylvania. She received a master's degree in biochemistry from the University of Rochester and a bachelor's degree in biochemistry from SUNY Geneseo. She is a specialist in biologics process chromatography, purifying a diversity of target molecules, including monoclonal antibodies and viral vectors.TBD

Register Free: https://www.biopharminternational.com/bp_w/mAB-Polishing-Solutions