Chromatograph Enables Fast Recovery of Target Compounds

The Prominence Ultra-Fast Preparative and Purification Liquid Chromatograph (UFPLC) from Shimadzu enables fast recovery of highly purified target compounds from complex samples including organic synthesis reaction mixtures and natural products. The Prominence UFPLC offers a single automated workflow that uses on-line fraction trapping as an alternative to traditional fraction collection, allowing elution of collected compounds in highly volatile organic solvents that can be easily evaporated, resulting in ultra-high-weight purity compounds in approximately 90 minutes. 

The Prominence UFPLC integrates traditional Prep LC with novel fraction trapping for up to five compounds of interest. Shimadzu’s Shim-pack C2P-H trapping column retains target compounds, allowing unwanted organic solvents, water, and additives to be flushed away. The Prominence UFPLC integrates Prep LC, fraction trapping, processing, and recovery into a single instrument and occupies approximately one-third of the bench space of conventional configurations. 

Shimadzu