August 12th 2025
The newly launched facility is located in The Woodlands, Texas, and will produce plasmid DNA as well as strengthen biopharma supply chains.
October 30th 2024
The collaboration aims to develop precision genetic medicines using ViaNautis’ proprietary polyNaut technology platform.
May 23rd 2024
The Mirus Bio acquisition will boost Merck KGaA’s viral vector manufacturing services.
May 6th 2024
The collaboration will target solid tumors using Poseida’s allogeneic CAR-T platform to develop convertibleCAR programs.
April 10th 2024
In back-to-back deals, Charles River will offer plasmid DNA manufacturing services for a gene therapy under development by Axovia Therapeutics and for a lead candidate being developed by Ship of Theseus.
The Status of the DNA Vaccine Field
Plasmid DNA-encoding proteins offer many advantages, which are now being used in clinical trials.
Managing Cell Line Instability and Its Impact During Cell Line Development
By considering stability as part of the cell line selection and cell banking paradigm, we can ensure that instability problems are not observed during clinical or commercial manufacturing.
Production Strategies for Antibody Fragment Therapeutics
Microbial systems such as E. Coli and yeasts are most effective for producing antibody fragments.
Recombinant Protein Production Yields from Mammalian Cells: Past, Present, and Future
A discussion of past achievements and future expectations of recombinant protein production yields from mammalian cells.