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Downstream Processing|

Upstream Processing

Deena Aguiar

Scientist of Purification Process Development at Medarex

Articles by Deena Aguiar

Precipitation of Process-Derived Impurities in Non-Protein A Purification Schemes for Antibodies

ByXiao-Ping Dai, PhD,Jue (Michelle) Wang, PhD,Deena Aguiar,Timothy Diehl,Alahari Arunakumari, PhD

October 2nd 2009

Precipitation prior to capture chromatography offers a simple, robust, and economical method to remove CHO host cell proteins and DNA.

Optimizing the Primary Recovery Step in Nonaffinity Purification Schemes for HuMAbs

ByJue (Michelle) Wang, PhD,Deborah Perkins,Deena Aguiar,Mark Watkins-Fischl,Timothy Diehl,Alahari Arunakumari, PhD

March 2nd 2008

An alternative approach to traditional Protein A schemes is comparable in overall efficiency, product recovery, and quality.

Latest Updated Articles

Precipitation of Process-Derived Impurities in Non-Protein A Purification Schemes for Antibodies
October 2nd 2009
Optimizing the Primary Recovery Step in Nonaffinity Purification Schemes for HuMAbs
March 2nd 2008