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Toshihiko Otsubo

Toshihiko Otsubo is principal scientist of Biologics Process Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Articles by Toshihiko Otsubo

Nikolai Sorokin/Stock.adobe.com - concept illustrating a needle that can cause pinholes

Proposing a New Method of Detecting Pinholes in Single-Use

ByToshihiko Otsubo,Shinji Tsuji,Yoshiaki Miko,Tetsuya Moritake,Osamu Shirokizawa,Takashi Kaminagayoshi

September 1st 2020

The increased use of single-use bags in biologic manufacturing poses the risk of pinholes and other defects that cannot currently be tested for.

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Proposing a New Method of Detecting Pinholes in Single-Use
September 1st 2020