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Tania Crombet

Havana

Cuba

Clinical Research Director at the Centro de Inmunología Molecular (Center for Molecular Immunology)

Articles

Manufacturing Process Development for an Epidermal Growth Factor-Based Cancer Vaccine

The Center for Molecular Immunology (Havana, Cuba) has been working on a novel cancer immunotherapy targeting the epidermal growth factor (EGF). The vaccine is composed of a chemical conjugate of EGF and a carrier protein (rP64k), designed to trigger an anti-EGF antibody response. The results of studies of molecular characterization, immunogenic activity, and clinical data are presented here.