Drug Digest: Engineering LNPs Beyond the Liver for Genetic Medicines

Ernesto Chico

Ernesto Chico is the technical director in the Technical Direction department at the Center of Molecular Immunology

Articles by Ernesto Chico

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The Center for Molecular Immunology (Havana, Cuba) has been working on a novel cancer immunotherapy targeting the epidermal growth factor (EGF). The vaccine is composed of a chemical conjugate of EGF and a carrier protein (rP64k), designed to trigger an anti-EGF antibody response. The results of studies of molecular characterization, immunogenic activity, and clinical data are presented here.