St John Skilton, PhD

St John Skilton, PhD, is the senior marketing manager at Waters Corporation.

Articles by St John Skilton, PhD

Capturing Conformational Changes in Biotherapeutics by Hydrogen Deuterium Exchange and UHPLC–MS

August 2nd 2010

By providing information on the relative accessibility of locations within a protein, HDX by mass spectrometry opens new windows into the higher order structure of biomolecules.

Rapid Assessment of Molecular Similarity between a Candidate Biosimilar and an Innovator Monoclonal Antibody Using Complementary LC–MS Methods

ByMartin Gilar, PhD,Weibin Chen, PhD,Deepalakshmi P. Dakshinamoorthy,Asish Chakraborty, PhD,St John Skilton, PhD,Ying Qing Yu, PhD,Hongwei Xie, PhD,Joomi Ahn

August 2nd 2010

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.

Latest Updated Articles

Capturing Conformational Changes in Biotherapeutics by Hydrogen Deuterium Exchange and UHPLC–MS
August 2nd 2010
Rapid Assessment of Molecular Similarity between a Candidate Biosimilar and an Innovator Monoclonal Antibody Using Complementary LC–MS Methods
August 2nd 2010